Ex Parte Schleifer et al - Page 5



                Appeal No. 2006-0103                                                                                 Page 5                    
                Application No. 10/172,892                                                                                                     

                (PDMS).  The method of attachment can be lamination, injection molding[,] gluing or any                                        
                other means, or the gasket layer can be held in place by the clamping force.”  Page 11,                                        
                paragraph [0158].                                                                                                              
                         Chen’s Figure 18 is reproduced below:                                                                                 













                The figure shows an “embodiment [in which] the cover slip can be flat and have a thick                                         
                gasket layer bonded to the bottom surface.  The gasket layer has openings which form                                           
                the wells.”  Page 11, paragraph [0162].                                                                                        
                         Chen’s Figure 19 is reproduced below:                                                                                 






                The figure is said to show how, “[i]n various embodiments, during hybridization, the cover                                     
                slip is placed upside down and such that the wells face up. . . . Sample or target liquid is                                   
                added to the wells (FIG. 19a).  Then the microarray substrate slide is placed upside                                           







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