Appeal No. 2006-0103 Page 10
Application No. 10/172,892
According to Schermer, Figure 2 is a perspective view and Figure 3A is a cross-sectional
view of a microarray apparatus. Column 5, lines 19-22. The figures show
[An] embodiment of the invention includ[ing] a stick-on cap or cover 50 and
a deflector 62. The cover can have a gasket region 52 and a top region
54. . . . Either the gasket region 52 or top region 54 of the cover 50 can be
deformable. . . . The deflector 62 is a mechanical device that can be used
to physically contact the cover 50 to deform the cover 50.
Column 5, lines 22-30.
Schermer discloses that
the cover 50 can be a two-piece embodiment having a gasket region 52
and a top region 54. . . . In still other embodiments, the function of the
gasket region 52 of the cover 50 can be provided by a structure where the
gasket portion of the cover 50 is permanently affixed to the microarray
substrate 10. . . .
The gasket region 52 of the cover 50 can be designed in a variety of
manners to accommodate the application. As indicated above, the gasket
52 can be permanently affixed to the top region 54, permanently affixed to
the substrate 10, or it can be a separate component.
Column 7, line 60, to column 8, line 13.
Schermer describes a method of using the apparatus shown in Figures 2 and 3A
as follows:
In operation, a volume of liquid reagent 56 is placed in the cover 50, and a
microarray substrate 10 is placed on top of the liquid reagent-filled cover 50
with the top surface 12 . . . of the substrate 10 facing downward, toward the
cover 50. The cover 50 can then be sealed onto the microarray substrate
10 by adhesive or mechanical clamping, or a combination of adhesive and
clamping. The gasket region 52 of the cover 50 contacts the microarray
substrate 10 in this embodiment, and a sealed reaction chamber 60 results
in the space between the top surface 12 of the microarray substrate 10 and
the cover 50.
Column 5, lines 30-40.
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Last modified: November 3, 2007