Ex Parte Beutler et al - Page 5


              Appeal No. 2006-0227                                                                   Page 5                 
              Application No. 10/121,264                                                                                    

              is deposited genomic DNA comprising more than one chromosome from a “vertebrate,                              
              invertebrate, plant, and prokaryotic” individual that belongs to “any group of individuals.”                  
                     When we give claim 40 its broadest reasonable interpretation consistent with the                       
              specification, we interpret it to be directed to a device comprising an object onto which                     
              genetic material can be deposited and a layer of a substance that can transport genetic                       
              material when the substance is moved, where the layer has deposited on or in it, at two                       
              separate positions, at least two chromosomes from the genomic DNA of any organism.                            
              2.  Anticipation                                                                                              
                     The examiner rejected claim 40 under 35 U.S.C. § 102(b) as anticipated by                              
              Chu.1  (Since the present application was filed in 2002 and Chu issued in 2004, the                           
              examiner’s citation of 35 U.S.C. § 102(b) appears to be a mistake.  However, the                              
              application that issued as the Chu patent was filed in 1998, so Chu appears to qualify                        
              as prior art under 35 U.S.C. § 102(e).  Appellants have not disputed that Chu is prior                        
              art.)                                                                                                         
                     The examiner reasoned that                                                                             
                     Chu discloses a device comprising a substrate (tray)[,] a transfer agent                               
                     layer (slide) and a first genetic material position and a second genetic                               
                     material position . . . comprising more than one chromosome from at least                              
                     one individual within a defined population (chromosome spread whereby                                  
                     the chromosomes are removed from the cells[;] i.e.[,] purified) and wherein                            
                     the first material position is separate from the second material position                              
                     (i.e.[,] different wells) (Column 32, line 35-Column 34, line 14).                                     
              Examiner’s Answer, pages 5-6.                                                                                 
                     We agree with the examiner that Chu’s Example 9 anticipates instant claim 40.                          
              Chu states that “[c]hromosomes can be examined for gross abnormalities such as                                







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