Ex Parte Morikawa et al - Page 2


                 Appeal No. 2006-3200                                                         Page 2                  
                 Application No.  10/196,428                                                                          
                               wherein R1 represents an organic group, X represents -CH2CH2- or                       
                        -CH=CH-, and R2 represents a hydrogen atom or an alkyl group, or a                            
                        lactone derivative thereof, or a salt thereof, as an active ingredient,                       
                               wherein the organic group is a 5 or 6 membered cyclic structure                        
                        containing 0 to 2 heteroatoms selected from the group consisting of N, O,                     
                        and S or a condensed ring thereof,                                                            
                               with the proviso that the compound of formula (1) is not                               
                        atorvastatin; and                                                                             
                               wherein said subject in need thereof suffers from rheumatoid                           
                        arthritis.                                                                                    

                        The references relied upon by the Examiner are:                                               
                 Bokoch     5,244,916   Sep. 14, 1993                                                                 
                 Partridge    6,403,637   Jun. 11, 2002                                                               
                 Chao     WO 01/22962  Apr.   5, 2001                                                                 
                 Luchetti et al. (Luchetti), “Expression and production of the long pentraxin PTX3                    
                 in rheumatoid arthritis (RA), Clin Exp. Immunol., Vol. 119, pp. 196-202 (2000).                      

                                             GROUND OF REJECTION                                                      
                        Claims 1-4 and 16-22 stand rejected under 35 U.S.C. § 103(a) as being                         
                 unpatentable over the combination of Chao, Bokoch, Partridge and Luchetti.                           
                        We affirm.                                                                                    


                                                CLAIM GROUPING                                                        
                        Appellants do not separately group or argue the claims before us on                           
                 appeal.  Accordingly the claims stand or fall together.  Since all claims stand or                   
                 fall together, we limit our discussion to representative independent claim 1.  37                    
                 C.F.R. § 1.192(c)(7) (rev. 2, May 2004).  Claims 2-4 and 16-22 will stand or fall                    
                 together with claim 1.  In re Young, 927 F.2d 588, 590, 18 USPQ2d 1089, 1091                         
                 (Fed. Cir. 1991).                                                                                    






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