Appeal 2007-0185 Application 10/305,281 It is well settled that there must be “clear and convincing evidence” of unobvious results in order to overcome a prima facie case of obviousness. In re Lohr, 317 F.2d 388, 392, 137 USPQ 548, 550-51 (CCPA 1963). In addition, the presentation of objective evidence of nonobviousness does not, in and of itself, mandate a conclusion of nonobviousness. The fact finder here, the Examiner, is entitled to his own ideas, within reason, as to what evidentiary facts will persuade him of unexpected results. Thus, whether the rebuttal evidence is sufficient to persuade the Examiner is an evidentiary matter left, within reason, to the trier of fact. In re Johnson, 747 F.2d 1456, 1460, 223 USPQ 1260, 1263 (Fed. Cir. 1984). We do not find Appellants’ evidence presented in the graph of Example 1, to be fully comparative and thus Appellants’ evidence does not mandate a conclusion of nonobviousness. While “discovery of an optimum value of a result effective variable in a known process is ordinarily within the skill of the art,” In re Boesch, 617 F.2d 272, 276, 205 USPQ 215, 219 (CCPA 1980), our reviewing court has found an exception to this general rule where “the parameter optimized was not recognized to be a result-effective variable,” In re Antonie, 559 F.2d 618, 620, 195 USPQ 6, 8- 9 (CCPA 1977). It is clear from appellant's data, that the result of lowering cholesterol is dependent upon the amount of pravastatin administered. However, we agree with the Examiner that the data before us indicates that one of ordinary skill in the art would have recognized that when the amount of pravastatin is increased, the expected benefit would be a further reduction in cholesterol levels. As indicated herein, we do not find Appellants’ data convincingly overcomes the Examiner's prima facie case of obviousness. In view of the above data discrepancies noted by the Examiner, we affirm the Examiner's prima facie case of obviousness. - 6 -Page: Previous 1 2 3 4 5 6 7 8 Next
Last modified: September 9, 2013