Ex Parte Pitman et al - Page 10

              Appeal 2007-0537                                                                     
              Application 10/102,902                                                               
              “homologous proteins show quite similar patterns of secondary chemical               
              shifts.”  (FF 9; see also FFs 10-17.)                                                
                    26.  The skilled artisan, applying Cornilescu’s teachings to search for        
              homologous proteins, would have had a reasonable expectation of                      
              identifying such proteins.  (See FF 9-17.)                                           
                    27.  The skilled artisan, faced with the problem of further                    
              implementing Cornilescu’s method on a computer, including the use of                 
              NMR to study chemical shifts, would have had reason to look to the general           
              teachings in the prior art, such as those of Gilhuijs.                               
                    28.  Appellants’ contested and undefined terms “features” and                  
              “descriptor,” and “context-adaptive scaling” are sufficiently broad to include       
              Cornilescu’s “chemical shifts” and “amino acid sequences,” and “k-values             
              scaling,” respectively.  (FFs 2-7, 9-11, 17-18.)                                     
                    29.  In addition, their broad definition of “fragment pairs” includes          
              Cornilescu’s amino acid residues separated by a dihedral bond.  (FFs 10-11,          
              14-17.)                                                                              
                                      DISCUSSION                                                   
              The § 103 Rejection Based on Cornilescu and Gilhuijs                                 
                    Our decision whether to affirm the rejection of claims 1-4, 6-10, 12-          
              19, 21-23, and 25-26 turns primarily on claim interpretation, more                   
              specifically the meaning of the terms “features,” “fragment pair,”                   
              “descriptor,” and “context-adaptive scaling.”  Except when applicants                
              expressly define their claim terms, “claims are given their broadest                 
              reasonable interpretation consistent with the specification.  [This]                 
              proposition ‘serves the public interest by reducing the possibility that claims,     
              finally allowed, will be given broader scope than is justified,’ . . . and it is     

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