Appeal 2007-0725
Reexamination Control 90/006,785
Patent 5,073,484
radioactivity of the zones, etc. For many reactions, detection is
signaled by a change in pH, and the detector may hence take the form
of a pH color indicator such as phenolphthalein, Nile Blue A, Thymol
Blue, and Methyl Violet. In other tests, one may detect the presence or
absence of the appropriate chemical moiety in a reaction zone by
observing whether a solid reaction product has settled upon the
succeeding spacer layer. Various detector mechanisms are known to
the art, and need not be described in detail. In the preferred
embodiment, however, which makes use of immunochemical reaction
between the analyte or the analyte and its derivative and the reactant,
often very small concentrations of analyte are to be measured and
accordingly a magnifying or amplifying mechanism may suitably be
employed. One such mechanism makes use of enzymes to promote
the reaction of a reaction product with a detector moiety to in turn
provide a visual color indication. …. A variety of modifications of
this procedure, of course, are known to the art. (Swanson at 8:47-68
through 9:1-30).
3. Patentee has not directed us to a specific definition of the following
claim terms:
“labeled”
“chemical moiety”
“reaction zone”
Weiss
4. Weiss states that “[t]his invention relates to an immunologically
specific reagent which can be employed to obtain a visual readout for
immunological reactions.” (Weiss at 1:32-34).
5. In the Weiss test, cellulosic particles are chemically linked to the
immunological counterpart of the material to be detected. (Weiss at 1:49-
55).
5
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