Ex Parte Li et al - Page 8



                Appeal 2007-1348                                                                               
                Application 10/650,253                                                                         
           1          A claimed invention is patentable if the subject matter of the claimed                   
           2    invention would not have been obvious to a person having ordinary skill in                     
           3    the art.  35 U.S.C. § 103(a); Graham v. John Deere Co. of Kansas City, 383                     
           4    U.S. 1 (1966).                                                                                 
           5          Facts relevant to a determination of obviousness include (1) the scope                   
           6    and content of the prior art, (2) any differences between the claimed                          
           7    invention and the prior art, (3) the level of skill in the art and (4) any                     
           8    relevant objective evidence of obviousness or non-obviousness.  Graham,                        
           9    383 U.S. at 17-18.                                                                             
          10                                                                                                   
          11          F.  Discussion                                                                           
          12                Lack of enablement and anticipation based on Bright                                
          13          In this particular appeal, the lack of enablement rejection and the                      
          14    anticipation rejection based on Bright may be considered together.                             
          15          Resolution of both rejections turns on a proper interpretation of                        
          16    claim 125.                                                                                     
          17          The Examiner determined that there was a lack of enablement and an                       
          18    anticipation by Bright based on her finding that a crystalline compound                        
          19    cannot maintain its crystalline structure in an aqueous media.  Examiner’s                     
          20    Answer, page 3.                                                                                
          21          The Examiner also determined that appellants’ “carrier” or “diluent”                     
          22    could be “sterile aqueous media.”  Examiner’s Answer, page 3.                                  
          23          Since a crystalline compound cannot maintain its crystalline structure                   
          24    in water, the Examiner reasoned that appellants’ disclosure is insufficient to                 
          25    enable one to make a combination of substantially pure Form F and water                        

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