Ex Parte Gordon et al - Page 10

                  Appeal 2007-2516                                                                                         
                  Application 10/302,553                                                                                   
                  ARDS.  The discovery of an optimum value of a results-effective variable in                              
                  a known process is normally obvious.  In re Antonie, 559 F.2d 618, 620, 195                              
                  USPQ 6, 8 (CCPA 1977); In re Aller, 42 CCPA 824, 220 F.2d 454, 105                                       
                  USPQ 233 (1955).                                                                                         
                         Appellants contend that “[u]sing the claimed particles to decrease an                             
                  oxygen index of a patient by at least 20%, is both new and unexpected”                                   
                  (Amended Br. 13).  “[W]hen unexpected results are used as evidence of                                    
                  nonobviousness, the results must be shown to be unexpected compared with                                 
                  the closest prior art.” In re Baxter Travenol Labs., 952 F.2d 388, 392, 21                               
                  USPQ2d 1281, 1285 (Fed. Cir. 1991).  Appellants have not presented any                                   
                  comparative evidence to establish that the claimed invention in comparison                               
                  to the prior art achieved unexpected results.                                                            
                         For the foregoing reasons, we affirm the rejection of claim 1.  Claims                            
                  2-14 fall with claim 1 because they were not separately argued.                                          
                         Claims 16-18                                                                                      
                         Claim 16 differs from claim 1 in reciting that the recited particles                              
                  comprise calcium.  Hafner ‘970 teaches that its lung surfactant can also                                 
                  contain calcium to set a favorable viscosity (Hafner ‘970, col. 3, ll. 45-47;                            
                  Findings of Fact 4; Answer 4).  We agree with the Examiner that it would                                 
                  have been obvious to include calcium with the surfactant for the reasons                                 
                  taught by Hafner ‘970.  Appellants do not identify a flaw in the Examiner’s                              
                  reasoning and we find none.  We affirm the rejection of claim 16.  Claims 17                             
                  and 18 fall with claim 16 because they were not separately argued.                                       





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