Ex Parte Gordon et al - Page 11

                  Appeal 2007-2516                                                                                         
                  Application 10/302,553                                                                                   
                         Claims 19-20                                                                                      
                         Claim 19 differs from claim 1 in reciting that the oxygen index of a                              
                  patient is decreased by “at least 40%” by inhaling the claimed composition                               
                  “in a plurality of inhalations over a 30 minute period.”  The claim also                                 
                  recites that particles comprise calcium.                                                                 
                         For the reasons discussed above for the limitation in claim 1 of                                  
                  “decreasing an oxygen index of a patient by at least 20%,” we conclude that                              
                  it would have been obvious to have optimized the administration conditions                               
                  to achieve the recited degree of oxygen index reduction.  We have                                        
                  considered Appellants’ arguments (Amended Br. 15-16), but they are no                                    
                  different than the arguments provided in support of the patentability of claim                           
                  1.  We do not find these arguments any more persuasive for claim 19.  We                                 
                  affirm the rejection of claim 19.  Claim 20 falls with claim 19 because it was                           
                  not separately argued.                                                                                   

                  Rejection under § 103 over Alliance by itself or in combination with                                     
                  Clements                                                                                                 
                         Claims 1-23 stand rejected under 35 U.S.C. § 103(a) as obvious over                               
                  Alliance by itself, or in combination with Clements (Answer).                                            
                         The Examiner contends that “[a]lthough [Alliance] does not provide                                
                  specific examples of powders containing DPPC and lung surfactant, from                                   
                  the guidance provided by [Alliance], it would have been obvious to one                                   
                  ordinary skill in the art to use lung surfactant and DPPC powders with                                   
                  claimed properties with a reasonable expectation of success, if the patient                              
                  requires a lung surfactant therapy” (Answer 8).  The Examiner also argues                                
                  that “[s]ince WO teaches a composition which is a combination of lung                                    

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