Appeal 2007-2955 Application 10/190,425 irrelevant. Wagner and Taylor use the same kinds of capture probes, e.g., antibodies, to form their microarrays (FF 17 and 22). They may differ in the manner in which the capture probes are attached to their respective substrates, but we find that one of ordinary skill in the art would have recognized these different types of attachment as conventional, alternative ways of immobilizing capture probes in a patterned microarray. “Section 103 forbids issuance of a patent when ‘the differences between the subject matter sought to be patented and the prior art are such that the subject matter as a whole would have been obvious at the time the invention was made to a person having ordinary skill in the art to which said subject matter pertains.’” KSR at 1734, 82 USPQ2d at 1391. We find that the Examiner has established a prima facie case that the invention of claim 1 would have been obvious over the prior art, which Appellants have not overcome by argument or evidence. As discussed above, claims 2-4, 6, 10, 31, and 33 fall with claim 1. Accordingly, the Examiner’s rejection of claims 1-4, 6, 10, 31, and 33 under 35 U.S.C. § 103(a) as unpatentable over Belov, Chang, Taylor, and Wagner is affirmed. 12Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 Next
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