Ex Parte Mohammed - Page 16

                Appeal 2007-3395                                                                               
                Application 10/260,733                                                                         
                Realizing this, the Examiner, for the first time,9 construes claim 1 as broad                  
                enough to encompass a bacterial genome, which does not contain intronic                        
                sequences (FF 44).  However, Bao is directed to measuring gene expression                      
                and chromosome abnormalities in the same tissue sample using array-based                       
                CGH (FF 18).  A unicellular bacterium cannot have multicellular tissues.                       
                Hence, the Examiner's response is contradictory to the teachings of Bao.                       
                Bao teaches a method using only two of the three genomic nucleic acid                          
                samples required by the method of claim 1 (FF 22-24).  Kuukasjärvi does                        
                not cure the deficiencies of Bao.  Since the Examiner has not established that                 
                the prior art (Bao and Kuukasjärvi) teach or suggest all of the limitations of                 
                claim 1, we will reverse the rejections of (i) claims 1-3, 5-7, 13-14, 18-25,                  
                28-31, 34-41, 46, 54-58, 61-62 and 86 under § 103(a) as obvious over Bao                       
                and Kuukasjärvi, and (ii) claims 47-49 under § 103(a) as obvious over Bao,                     
                Kuukasjärvi and Bradley.                                                                       
                IV. Summary                                                                                    
                      In view of the record and for the reasons given, it is                                   
                      ORDERED that the rejection of claims 1-3, 5-7, 13-14, 18-25, 28-31,                      
                34-41, 46, 54-58, 61-62 and 86 under 35 U.S.C. § 103(a) as obvious over the                    
                combined teachings of Bao and Kuukasjärvi is REVERSED;                                         
                      FURTHER ORDERED that the rejection of claims 47-49 under 35                              
                U.S.C. § 103 (a) as obvious over the combined teaches of Bao, Kuukasjärvi,                     
                and Bradley is REVERSED; and                                                                   
                                                                                                               
                9 The Board’s review of the claims on appeal is not an independent analysis                    
                in the first instance.  The Examiner should set forth sufficient factual                       
                findings and reasoning supporting claim construction in the first instance, to                 
                permit a meaningful evaluation of the claimed invention vis-à-vis the                          
                applied prior art.                                                                             

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