Appeal No. 93-3369
Application 07/344,179
The column-associated particulate support (hereinafter the
column support) contains materials critical to the binding of a
molecule of interest such that it can be separated from a sample
added to the device. The sleeve-associated particulate support
(hereinafter the sleeve support) contains material critical to
detection of the binding should it take place in the support
contained in the column.
All of the claims are limited to the use of antibodies and
labeled analytes on the column support. The antibody is
immobilized on this column support. The molecule of interest
that the device is designed to detect is referred to throughout
the claims as the “analyte.” The term “analyte label” in the
claims refers to a material that has been bound to the
immobilized antibody on the column support, in which the analyte,
or an analog thereof, is chemically labeled with a material which
itself has a visible color or which can be reacted with other
compounds to produce a compound which has a visible color. The
amount of “analyte label” on the column support is high enough to
saturate
substantially all of the binding sites of the antibody
immobilized on the support.
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