Ex parte CARTER et al. - Page 2




                Appeal No. 95-4493                                                                                                            
                Application 07/756,646                                                                                                        


                         The subject matter on appeal is directed to the antibiotic                                                           
                LL-E19020 Alpha , its composition and method of use in treating                                                               
                                         1                                                                                                    
                infections.  The antibiotic LL-E19020 Alpha  is the C-21 epimer         1                                2                    
                of known antibiotic LL-E19020 Alpha (specification, page 3).  The                                                             
                subject matter on appeal is adequately illustrated by appealed                                                                
                claim 1, which is reproduced and attached to this decision as an                                                              
                Appendix.                                                                                                                     
                         The references relied upon by the examiner are:                                                                      
                Carter et al. (Carter)        4,705,688       Nov. 10, 1987                                                                   
                Carter et al. (Carter II), “LL-E19020" and $, Novel Growth                                                                    
                Promoting Agents: Isolation, Characterization and Structures”, 41                                                             
                The Journal of Antibiotics, no. 10, 1511-1514 (October 1988).                                                                 
                         Claims 1, 4 and 5 stand rejected under 35 U.S.C. § 103 as                                                            
                unpatentable over Carter II.  Claim 1 stands rejected under 35                                                                
                U.S.C. § 102(b) as anticipated by Carter .  We reverse both        3                                                          
                stated rejections.                                                                                                            




                         2An epimer is an isomer which differs from the compound                                                              
                with which it is being compared only in the relative positions of                                                             
                an attached hydrogen and hydroxyl.  The isomerism may be                                                                      
                represented as -HCOH- and -HOCH-.  See The Condensed Chemical                                                                 
                Dictionary, page 343 (Ninth Ed., Van Nostrand Reinhold Company,                                                               
                1977).                                                                                                                        
                         3This rejection was a new ground of rejection made for the                                                           
                first time on page 5 of the examiner’s answer.                                                                                
                                                                      2                                                                       





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