Appeal No. 95-4493 Application 07/756,646 OPINION A. The Rejection under 35 U.S.C. § 103 The claimed antibiotic compound LL-E19020 alpha (hereafter 1 “alpha-1") is the C-21 epimer of the known antibiotic LL-E19020 alpha (hereafter “alpha”). Alpha-1 is prepared by the process set forth on pages 10-13 of the specification. Carter II describes the discovery of antibiotic alpha and its preparation on page 1511. From the properties recited for alpha in the Carter II article and those properties of alpha-1 recited in appealed claim 1, it is apparent that the examiner and appellants agree that alpha and alpha-1 are different compounds but have the same structural formula. As stated by the examiner, the “sole difference” between the prior art and the claimed compound “lies in the configuration of the trisaccharide moiety at the C-21 position” (answer, page 4). The examiner concludes that the claimed compound “is rendered obvious” because the prior art compound is “structurally similar” and both “possess similar antibacterial properties” (answer, page 4). The examiner states that “the courts have consistently held that if the claimed invention is structurally 3Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 NextLast modified: November 3, 2007