Appeal No. 96-2137
Application 07/668,920
The three monoclonal antibodies identified by an asterisk in Table 1 are stated at page
21 of the specification to be “[t]hree candidate antibodies.” Furthermore, the
specification puts the data reported in Table 1 in perspective in the paragraph bridging
pages 22-23 of the specification as follows:
In order to understand the significance of the data in Table 1, it is
important to realize that even a “live” in vitro culture will contain a
relatively large proportion of necrotic cells, as opposed to a population of
similar cells in vivo. Thus, some binding to the “live” cell culture can be
expected, even with an antibody that is specific to only insoluble
intracellular antigen. It should also be recognized that even though the
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