Appeal No. 93-4005 Application 07/795,158 31. The examiner found that Epstein teaches enhanced recovery of riboflavin by degradation of the undesired cellular macromolecules with enzymes. Examiner's Answer (Paper No. 10, page 3). The examiner recognized that Epstein "does not teach utilizing the cells' own enzymes but adds enzymes to the suspension." Id. Babayan was used to teach that under appropriate conditions, i.e., pH and temperature "yeast cell autolysis" can be induced. Id. According to the examiner, it would have been obvious to use the teachings of Babayan to achieve autolysis, thereby making it unnecessary to add enzymes in accordance with the process suggested by Epstein. 32. The examiner refers to "yeast" cells several times in Examiner's Answer. See pages 3 and 4. 33. Applicant also characterizes Ashbya gossypii as a "yeast" on several pages of the BRIEF ON APPEAL (Paper No. 9), e.g., "the yeast Ashbya gossypii" (page 1); "[a]ccording to the present invention, the riboflavin is released from the yeast cells following fermentation" (page 2). 34. Both the examiner and applicant have based their respective arguments for unpatentabilty and patentability over - 15 -Page: Previous 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NextLast modified: November 3, 2007