Appeal No. 93-4005
Application 07/795,158
the combination of Epstein and Babayan on an incorrect
characterization of Ashbya gossypii as a yeast, when in fact
it is a filamentous fungi.
Level of skill in the art
35. In addition to the information revealed in the
prior art documents discussed above, one having ordinary skill
in the art would have knowledge of the following.
36. One having ordinary skill in the art, as of
applicant's filing date, would consider Ashbya gossypii to be
a filamentous fungi, not a yeast.
37. Reyes et al. report that "[i]n the filamentous
fungi the lytic enzymes involved in the degradation of the
cell wall and storage polysaccharides show increased activity
in the culture fluid during the autolytic phase of growth.
Reyes, "Lytic enzymes in the autolysis of Schizophyllum
commune with special reference to 1,3-"-glucanase," Can. J.
Microbiol., Vol. 26, page 1120 (1980).
38. Reyes goes on to state that "[t]hese enzymes
also occur in the mycelium and in the cell wall" (id.).
39. Reyes indicates that after autolysis has
proceeded for some time, "carbohydrates may accumulate and
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