Interference No. 102,572
The Boss et al. arguments are without merit. It is true that the present rules do not
require Boss et al. to notify Cabilly et al. of the oversight. As a matter of courtesy, Boss et
al. could have notified Cabilly et al. of the omission when the exhibits were served. We find
no prejudice to Boss et al. by entering the omitted exhibits into the record.
II.
Background:
Immunoglobulins (Ig), also called antibodies, are protein molecules produced in
vertebrates by B cells in response to foreign antigenic agents. (Boss et al. patent, column
1, lines 60-64, Cabilly et al. specification, page 1). The basic structure of all
immunoglobulin molecules is a unit consisting of two identical light (L) polypeptide chains
of molecular weight of approximately 23,000 daltons and two identical heavy (H)
polypeptide chains of molecular weight 53,000-70,000 daltons, shaped to form a Y:
Each H and L chain is held together by disulfide bonds to form a monomer, and the two
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