Ex parte SAITO et al. - Page 3




          Appeal No. 94-4009                                   Paper No. 32           
          Application No. 07/953,716                                 Page 3           
               Claims 22, 23, and 24, which depend from claim 11 via                  
          claims 19, 20, and 21,  respectively, identify compounds for3                                                     
          use in the method as follows:                                               
                    22. The method of claim 19, wherein said                          
               compound is (E)-3,5-dihydroxy-7-[4'-(4"-                               
               fluorophenyl)-2'-cyclopropyl-quinolin-3'-yl]hept-6-                    
               enoic acid, a compound having such carboxylic acid                     
               condensed with hydroxy at the 5-position to form a                     
               lactone, a sodium or calcium salt of such carboxylic                   
               acid, or a C  alkyl ester of such carboxylic acid.                     
                           1-3                                                        
                    23. The method of claim 20, wherein said                          
               compound is (E)-3,5-dihydroxy-7-[6'-cyclopropyl-4'-                    
               (4"-fluorophenyl)-1',3'-dimethylpyrazolo[3,4-                          
               b]pyridin-5'-yl]hept-6-enoic acid, a compound having                   
               such carboxylic acid condensed with hydroxy at the                     
               5-position to form a lactone, a sodium or calcium                      
               salt of such carboxylic acid, or a C  alkyl ester of                   
                                                   1-3                                
               such carboxylic acid.                                                  
                    24. The method of claim 21, wherein said                          
               compound is (E)-3,5-dihydroxy-7-[6'-cyclopropyl-3'-                    
               ethyl-4'-(4"-fluorophenyl)-2'-methylthieno[2,3-                        
               b]pyridin-5'-yl]hept-6-enoic acid, a compound having                   
               such carboxylic acid condensed with hydroxy at the                     
               5-position to form lactone, a sodium or calcium salt                   
               of such carboxylic acid, or a C  alkyl ester of such                   
                                              1-3                                     
               carboxylic acid.                                                       
               At the hearing, Appellants' counsel conceded that                      
          compounds of formula (I) are not new.  This concession is                   
          consistent with our understanding that the genus of compounds               
          in the claimed method includes compounds taught in the                      
          Fujikawa patents.  Specifically, compound I-517 (Table I) of                

               3    These claims further limit claim 11 only by further               
          defining the compound, not by adding additional steps.                      





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