Ex parte SAITO et al. - Page 4




          Appeal No. 94-4009                                   Paper No. 32           
          Application No. 07/953,716                                 Page 4           
          the '930 patent is within the subgenus of claim 22; compound                
          I-1-5 (Table 9) of the '999 patent is within the subgenus of                
          claim 23; and compound I-1-7 (Table 7) of the '698 patent is                
          within the subgenus of claim 24.                                            
               The examiner rejected all pending claims under 35 U.S.C.               
          § 103 as having been obvious in view of each of the three                   
          Fujikawa patents in combination with Avery's Drug Treatment                 
          594-595 (3d ed., Trevor M. Speight ed. 1987) ("Speight").                   
               Appellants submitted as evidence in the record a                       
          declaration from co-inventor Masaki Kitahara (Paper No. 16)                 
          and an excerpt from W.C. Bowman & M.J. Rand, Textbook of                    
          Pharmacology, Second Edition, pp. 23.61-23.62 (1980)                        
          ("Bowman").                                                                 
               The claims directed to specific dose ranges and methods                
          of administration (claims 15-17) were not separately argued                 
          (Paper No. 18 at 3).  Nevertheless, we find that the claimed                
          methods of administration and dosages are disclosed in the                  
          Fujikawa patents ('930 at 12:31-33 and 52-54; '999 at 26:54-56              
          and 27:7-9; '698 at 28:35-37 and 56-57).                                    
                                     DISCUSSION                                       
               To determine patentability under 35 U.S.C. §§ 102  and                 
          103, one must first construe the claims.  Key Pharm. Inc. v.                
          Hercon Labs., 161 F.3d 709, 713, 48 USPQ2d 1911, 1915 (Fed.                 





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