Ex parte CONE et al. - Page 6




             Appeal No. 95-2710                                                                                   
             Application 08/011,837                                                                               


                    Appellants provide figures which show that appellants’                                        
             antibodies agglutinate sperm and other cells (page 8, lines 2-                                       
             28; page 17, lines 18-20), and state that all five tested                                            
             antibodies coagulated virtually all cells present in semen,                                          
             either directly or by binding to factors secreted by the                                             
             seminal vesicles (page 17, line 30 - page 18, line 2).  Also,                                        
             Isojima discloses (page 67) that H6-3C4 has strong sperm                                             
             immobilizing and agglutinating activities.                                                           
                    The examiner provides no evidence or sound technical                                          
             reason which indicates that one of ordinary skill in the art                                         
             would have questioned the objective truth of the statements in                                       
             appellants’ specification that their pan semen antibodies bind                                       
             to cells and pathogens in semen, including cells that carry                                          
             AIDS, thereby trapping the cells and pathogens.  Hence, the                                          
             examiner has not carried his initial burden of establishing a                                        
             prima facie case of lack of utility.                                                                 
                    For the above reasons, we do not sustain the rejection                                        
             under 35 U.S.C. § 101.                                                                               
                        Rejection under 35 U.S.C. § 112, first paragraph                                          
                    The examiner argues that there is no evidence of record                                       


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