Ex parte CONE et al. - Page 7




             Appeal No. 95-2710                                                                                   
             Application 08/011,837                                                                               


             of an antibody which can agglutinate sexually transmitted                                            
             disease pathogens and sperm (answer, pages 4, 7 and 8).                                              
             Appellants argue that their specification discloses five                                             
             antibodies which are useful for carrying out the claimed                                             
             methods and provides six criteria for screening additional pan                                       
             semen antibodies (brief, pages 7-10).  The specification,                                            
             appellants argue (brief, page 9), discloses at page 16, lines                                        
             26-33, antibodies which immobilize sperm and also immobilize                                         
             virtually all other cells in semen by coagulating them with                                          
             the sperm (see also, reply brief, pages 4-5).                                                        
                    With respect to enablement, a predecessor of our                                              
             appellate reviewing court stated in In re Marzocchi, 439 F.2d                                        
             220, 223-24, 169 USPQ 367, 369-70 (CCPA 1971):                                                       
                          [A] specification disclosure which contains a                                           
                    teaching of the manner and process of making and                                              
                    using the invention in terms which correspond in                                              
                    scope to those used in describing and defining the                                            
                    subject matter sought to be patented must be taken                                            
                    as in compliance with the enabling requirement of                                             
                    the first paragraph of § 112 unless there is reason                                           
                    to doubt the objective truth of the statements                                                
                    contained therein which must be relied on for                                                 
                    enabling support. . . .                                                                       
                                                    . . . .                                                       
                    . . . it is incumbent upon the Patent Office,                                                 

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