Ex parte COLE et al. - Page 12




                 Appeal No. 98-1591                                                                                                                     
                 Application 08/417,625                                                                                                                 


                 26).  This argument is not convincing because anticipation is                                                                          
                 the epitome of obviousness, see In re Fracalossi, 681 F.2d                                                                             
                 792, 794, 215 USPQ 569, 571 (CCPA 1982) (“Though the PTO spoke                                                                         
                 in terms of obviousness, the lack of novelty from the claimed                                                                          
                 invention is a fact.  Moreover, lack of novelty is the                                                                                 
                 ultimate of obviousness. ... An old composition cannot be                                                                              
                 converted into an unobvious composition simply by inept                                                                                
                 references to obviousness.”), and evidence of unexpected                                                                               
                 results is not relevant to anticipation.  See In re Malagari,                                                                          
                 499 F.2d 1297, 1302, 182 USPQ 549, 553 (CCPA 1974).                                                                                    
                 Accordingly, we sustain the examiner’s rejection of claims 36,                                                                         
                 37 and 40-45 under 35 U.S.C. § 103.                                                                                                    
                                                  Rejection of claims 38 and 39                                                                         
                                                         under 35 U.S.C. § 103                                                                          
                          Claims 38 and 39 recite, respectively, clavulanic acid                                                                        
                 and potassium clavulanate, each being free of recited                                                                                  
                 compounds which, appellants’ specification states (page 3,                                                                             
                 lines 4-9), are antibiotics produced by Streptomyces                                                                                   
                 clavuligerus, which is the microorganism which produces                                                                                
                 clavulanic acid (specification, page 1, lines 1-3).                                                                                    
                          The examiner argues that since clavulanic acid was                                                                            

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