Interference No. 103,197
obtain a saturation reading because of the motion
artifact. That's been my experience.
We are of the view that even if, as Morrison contends, the
test apparatus actually was measuring the oxygen saturation of
the arterial blood in Dr. Morrison's forearm tissue, the light
modulation caused thereby may have been significantly affected
by the light modulation due to the variations the distance
between the needle ends, which is sufficient reason to doubt
the accuracy of the oxygen saturation readings. Consequently,
this is an additional reason why the February tests did not
constitute an actual reduction to practice. However, this
problem does not make the November 1987 designs inoperative,
because in those designs the distance between the ends of the
needles is fixed.
(d) Motion artifacts due to fiber optic movement
Falkowski also testified that when optical fibers are107
bent, the light intensity is modulated as the fiber's geometry
changes, and that this effect plays a significant role
if the accuracy of the light transmission is high, i.e.,
if modulation of 1% or less is a problem. This is
exactly the case in pulse oximetry, since a modulation in
the range of 0.1-1% is exactly the AC signal range.
BR 29-30, ¶ 10.107
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