Ex parte SHIMAZAKI et al. - Page 3




          Appeal No. 1997-0472                                                        
          Application No. 08/259,152                                                  


          remain soluble even in relatively low salt concentrations"                  
          (page 4 of brief).                                                          


               Appellants submit at page 2 of the brief that "[t]he                   
          rejected claims do not stand or fall together" and that                     
          "[e]ach claim is believed to define a separately patentable                 
          invention."  However, the ARGUMENTS section of appellants'                  
          brief fails to advance any argument that is reasonably                      
          specific to any particu-lar claim on appeal.  Accordingly, all              
          the appealed claims stand or fall together with claim 26.                   
               Appealed claims 26-30 and 32 stand rejected under 35                   
          U.S.C. § 103 as being unpatentable over D'H.                                
               We have thoroughly reviewed each of appellants' arguments              
          for patentability.  However, we concur with the examiner that               
          the claimed subject matter would have been obvious to one of                
          ordinary skill in the art within the meaning of § 103 in view               
          of the applied prior art.  Accordingly, we will sustain the                 
          examiner's rejection.                                                       
               Appellants do not dispute the examiner's factual                       
          determina-tion that D'H discloses an aqueous solution of a                  
          plasminogen activator and appellants' anionic polymer, dextran              
                                          3                                           





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