Ex parte GRAHAM - Page 4




          Appeal No. 1997-1705                                                        
          Application 08/211,352                                                      


                           Rejection under 35 U.S.C. § 103                            
               Appellant states that no claim is made for separate                    
          patentability (brief, page 4).  Thus, the claims stand or fall              
          together and we limit our discussion to one claim, i.e.,                    
          claim 17.  See In re Ochiai, 71 F.3d 1565, 1566 n.2, 37 USPQ2d              
          1127, 1129 n.2 (Fed. Cir. 1995); 37 CFR § 1.192(c)(7)(1995).                
               In order for a prima facie case of obviousness to be                   
          established, the applied prior art must have provided one of                
          ordinary skill in the art with both a motivation to carry out               
          appellant’s claimed method and a reasonable expectation of                  
          success in doing so.  See In re Vaeck, 947 F.2d 488, 493, 20                
          USPQ2d 1438, 1442 (Fed. Cir. 1991); In re O’Farrell, 853 F.2d               
          894, 902, 7 USPQ2d 1673, 1680 (Fed. Cir. 1988).                             
               Jankovic discloses under “Other Potential Indications”                 
          (page 1191) that “[t]he effects of botulinum toxin on                       
          spasticity in children with cerebral palsy are also being                   
          studied” and, under “Strabismus and Other Disorders of Ocular               
          Motility” (page 1187), that “children under seven years of age              
          may require light ketamine anesthesia and restraint” when                   
          treated with botulinum toxin.  Jankovic states that he refers               

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