Ex parte GRAHAM - Page 10




          Appeal No. 1997-1705                                                        
          Application 08/211,352                                                      


          section of the statute.                                                     
                  Rejection under 35 U.S.C. § 112, first paragraph                    
               The examiner argues that there is inadequate written                   
          descriptive support in appellant’s original specification for               
          “having a duration greater than a clinical activity of said                 
          presynaptic neurotoxin” in claims 1, 6 and 17, “having a                    
          duration greater than a clinical activity of said botulinum                 
          toxin” in claim 7, and “having a clinical activity of about                 
          four months” in claim 10.                                                   
               We do not find in appellant’s briefs a challenge to the                
          rejection based on the language in claim 10.  We therefore                  
          affirm the rejection under 35 U.S.C. § 112, first paragraph,                
          of claim 10 and claims 11 and 12 which depend therefrom.                    
               Claims 1 and 7 require that the promotion of normal                    
          muscle growth has a duration greater than the clinical                      
          activity of the presynaptic neurotoxin or botulinum toxin.                  
          Appellant argues (brief, page 12; reply brief, page 8) that                 
          this language is supported by the statements in the                         
          specification that “such functional improvements persist when               
          the tone reducing effects of the toxin have worn off” (page 4)              


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