Ex parte GRAHAM - Page 11




                     Appeal No. 1997-1705                                                                                                                                              
                     Application 08/211,352                                                                                                                                            


                     and “[a]t this stage the effects of the toxin had clinically                                                                                                      
                     worn off and it was found that the knee flexed to the same                                                                                                        
                     extent in swing that it did prior to injection” (page 10).                                                                   7                                    
                     These statements, however, pertain to functional improvements                                                                                                     
                     and knee flexure, whereas claims 1 and 7 require that normal                                                                                                      
                     muscle growth continues to be promoted after the clinical                                                                                                         
                     activity of the toxin ends.  Appellant has not pointed out,                                                                                                       
                     and we do not find, written descriptive support in the                                                                                                            
                     original specification for this claim requirement.                                                                                                                
                     Accordingly, we affirm the rejection under 35 U.S.C. § 112,                                                                                                       
                     first paragraph, of claim 1 and claims 2-4 which depend                                                                                                           
                     therefrom, and claim 7 and claims 15 and 16 which depend                                                                                                          
                     therefrom.  Also, this is an additional reason for affirming                                                                                                      
                     the rejection under 35 U.S.C. § 112, first paragraph, of claim                                                                                                    
                     10 which depends from claim 7.                                                                                                                                    
                                Claims 6 and 17 require that the relief from arrested                                                                                                  
                     muscle growth has a duration which is greater than the                                                                                                            
                     clinical activity of the presynaptic neurotoxin.  This                                                                                                            

                                7 The article relied upon by appellant on page 14 of the                                                                                               
                     brief is not part of the specification and is not prior art.                                                                                                      
                     Thus, we give it no weight in our determination of whether the                                                                                                    
                     specification complies with 35 U.S.C. § 112, first paragraph.                                                                                                     
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