Ex parte GRAHAM - Page 9




                     Appeal No. 1997-1705                                                                                                                                              
                     Application 08/211,352                                                                                                                                            


                     as little as a fraction of a second.5                                                                                                                             
                                As for Example 2, appellant argues that it was unexpected                                                                                              
                     that injection of intermuscular botulinum toxin A during the                                                                                                      
                     growth period of the hereditary spastic mouse allowed normal                                                                                                      
                     longitudinal muscle growth to take place (reply brief, page                                                                                                       
                     6).  This argument is not persuasive for the reasons given                                                                                                        
                     regarding Case Study 1 and also because appellant has not                                                                                                         
                     established that results for mice are indicative of results                                                                                                       
                     for a human.              6                                                                                                                                       
                                For the above reasons we conclude, based upon the                                                                                                      
                     preponderance of the evidence, that the method recited in                                                                                                         
                     appellant’s claim 17 would have been obvious to one of                                                                                                            
                     ordinary skill in the art within the meaning of 35 U.S.C.                                                                                                         
                     § 103.  Consequently, we affirm the rejection under this                                                                                                          



                                5 See In re Grasselli, 713 F.2d 731, 743, 218 USPQ 769,                                                                                                
                     778 (Fed. Cir. 1983); In re Clemens, 622 F.2d 1029, 1035, 206                                                                                                     
                     USPQ 289, 296 (CCPA 1980).                                                                                                                                        
                                6 When we give appellant’s claim 17 its broadest                                                                                                       
                     reasonable interpretation in view of the specification and the                                                                                                    
                     prior art, see In re Kroekel, 504 F.2d 1143, 1146, 183 USPQ                                                                                                       
                     610, 612 (CCPA 1974); In re Moore, 439 F.2d 1232, 1235, 169                                                                                                       
                     USPQ 236, 238-39 (CCPA 1971), we conclude that “juvenile                                                                                                          
                     patients” refers to human juvenile patients.                                                                                                                      
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