Appeal No. 1998-0244
Application No. 08/531,890
Szycher and Sablotsky to overcome the first deficiency and
Morgan and Blackford to overcome the second.
Szycher discloses a transdermal patch 10 composed of a
substrate 12, a pressure sensitive adhesive 14, a drug
releasing member 16 and optionally a second layer of adhesive
18, these elements being arranged as shown in Figure 3. The
optional second layer of adhesive 18 allows the patch to be
adhered to the targeted site (see column 4, lines 45 through
54). Szycher indicates in very general terms that the patch
is made by successively adding its constituent layers to the
substrate 12 (see column 6, lines 40 through 59).
Sablotsky discloses “a dermal composition suitable for
use in the transdermal delivery of drugs, which composition
permits a high loading of medicament as well as a low loading
of medicament into the formulation while maintaining
acceptable shear, tack and peel adhesive properties” (column
2, lines 5 through 10). As for the system in which this
composition is used, Sablotsky states that
[t]he transdermal drug delivery system of this
invention has a defined geometric shape, with a
release liner on one side. Removal of the liner
exposes the pressure sensitive adhesive that
functions as the drug carrier and as the means of
applying the system to the patient. The pressure-
5
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