Appeal No. 1997-2510 Application No. 07/868,539 combined references of Vickers et al., Bielinska et al., Sakata et al., Uhlmann et al., and Inouye ….” Vickers, however, is not part of this rejection. With regard to the modification of Bielinska with Sakata, absent appellant’s disclosure, the examiner has not identified any portion of the references relied upon that suggests to a person of ordinary skill in the art to remove the loop from Sakata’s stem-loop construct and place it on the construct of Bielinska. As set forth in In re Kotzab, 217 F.3d 1365, 1369-70, 55 USPQ2d 1313, 1316 (Fed. Cir. 2000): A critical step in analyzing the patentability of claims pursuant to section 103(a) is casting the mind back to the time of invention, to consider the thinking of one of ordinary skill in the art, guided only by the prior art references and the then-accepted wisdom in the field. … Close adherence to this methodology is especially important in cases where the very ease with which the invention can be understood may prompt one “to fall victim to the insidious effect of a hindsight syndrome wherein that which only the invention taught is used against its teacher.” … Most if not all inventions arise from a combination of old elements. … Thus, every element of a claimed invention may often be found in the prior art. … However, identification in the prior art of each individual part claimed is insufficient to defeat patentability of the whole claimed invention. … Rather, to establish obviousness based on a combination of the elements disclosed in the prior art, there must be some motivation, suggestion or teaching of the desirability of making the specific combination that was made by the applicant. [citations omitted] 24Page: Previous 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 NextLast modified: November 3, 2007