Ex Parte CARMAN - Page 24



                    Appeal No. 1997-2510                                                                                                    
                    Application No. 07/868,539                                                                                              

                    combined references of Vickers et al., Bielinska et al., Sakata et al., Uhlmann et                                      
                    al., and Inouye ….”  Vickers, however, is not part of this rejection.                                                   
                            With regard to the modification of Bielinska with Sakata, absent                                                
                    appellant’s disclosure, the examiner has not identified any portion of the                                              
                    references relied upon that suggests to a person of ordinary skill in the art to                                        
                    remove the loop from Sakata’s stem-loop construct and place it on the construct                                         
                    of Bielinska.                                                                                                           
                            As set forth in In re Kotzab, 217 F.3d 1365, 1369-70, 55 USPQ2d 1313,                                           
                    1316 (Fed. Cir. 2000):                                                                                                  
                            A critical step in analyzing the patentability of claims pursuant to                                            
                            section 103(a) is casting the mind back to the time of invention, to                                            
                            consider the thinking of one of ordinary skill in the art, guided only                                          
                            by the prior art references and the then-accepted wisdom in the                                                 
                            field. … Close adherence to this methodology is especially                                                      
                            important in cases where the very ease with which the invention                                                 
                            can be understood may prompt one “to fall victim to the insidious                                               
                            effect of a hindsight syndrome wherein that which only the                                                      
                            invention taught is used against its teacher.”                                                                  
                                                                    …                                                                       
                            Most if not all inventions arise from a combination of old elements.                                            
                            … Thus, every element of a claimed invention may often be found                                                 
                            in the prior art. … However, identification in the prior art of each                                            
                            individual part claimed is insufficient to defeat patentability of the                                          
                            whole claimed invention. … Rather, to establish obviousness based                                               
                            on a combination of the elements disclosed in the prior art, there                                              
                            must be some motivation, suggestion or teaching of the desirability                                             
                            of making the specific combination that was made by the applicant.                                              
                            [citations omitted]                                                                                             







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