VISSER et al v. HOFVANDER et al - Page 52




          Interference 103,579                                                        
          as SEQ ID No. 1, 2, or 3 in the case of Hofvander’s claims, or a            
          larger fragment of the PGBSS gene, including as a subfragment               
          thereof, a sequence identified as a full length PGBSS cDNA or               
          genomic DNA sequence in the case of Visser’s claims.  We must               
          give the language of the parties’ claims its broadest reasonable            
          interpretation consistent with the supporting disclosures.                  
               According to the respective specifications, a gene construct           
          or vector “comprising” a PGBSS gene fragment selected from the              
          group consisting of SEQ ID No. 1, 2, or 3, or an upstream                   
          promoter sequence and a sequence identified as SEQ ID No. 1, 2,             
          or 3 of Hofvander’s claims, or a gene construct “containing” a              
          full length PGBSS cDNA or genomic DNA sequence coding for PGBSS             
          in reverse orientation of Visser’s claims, does not generally               
          read on larger fragments of the PGBSS gene, each of which                   
          includes as a subfragment thereof, a sequence identified as SEQ             
          ID No. 1, 2, or 3 or an upstream promoter sequence and a sequence           
          identified as SEQ ID No. 1, 2, or 3 in the case of Hofvander’s              
          claims, or generally read on larger fragments of the PGBSS gene             
          which includes as a subfragment thereof, a sequence identified as           
          a full length PGBSS cDNA or genomic DNA sequence in the case of             
          Visser’s claims.  Hofvander’s specification would have led                  
          persons having ordinary skill in the art to understand that other           
          sequences which are PGBSS fragments substantially larger in                 
          size than the sequences identified as SEQ ID Nos. 1, 2 and 3 in             
                                        -52-                                          





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