Interference 103,579
the coding region of the GBSS gene depicted below includes a
HindIII-SpeI fragment (HR 312 (VDX 10), Fig. 2 “Result of
restriction analysis. GBSS coding region including introns are
marked in a darker tone.”):
NsiI HpaI EcoRI SstI SpeI
HindIII NsiI HindIII SstI
I II I I I I I I .
VII. We find that the 2961 bp complete genomic DNA sequence
Leij depicts at the top of VDX 15/HDX 8, Kuipers’ 3.0 kb full
length genomic BamHI-SpeI fragment designated SUB10 said to
include a HindIII-SpeI subfragment (VDX 4, p. 748, Fig. 1A/
HR 339, Fig. 1A), Visser’s 3.0 kb HindIII-SpeI fragment said to
contain the complete coding region of the GBSS gene, and the GBSS
coding region depicted in Figure 2 of Hofvander’s involved
application as including a HindIII-SpeI fragment (HR 312/VDX 10),
all contain the complete coding region of the GBSS gene.
VIII. We interpret the phrases “full length potato . . .
genomic DNA sequence coding for PGBSS” and “full length . . .
PGBSS . . . genomic DNA” of the claims of Visser’s involved
application to mean the complete coding region of the GBSS gene
(1) which Kuipers’ 3.0 kb BamHI-SpeI fragment SUB10 is said to
include (VDX 4, p. 748, Fig. 1A; HR 339, Fig. 1A); (2) by which
Kuipers’, Visser’s, and Hofvander’s HindIII-SpeI fragment is said
to be encompassed; (3) to which Leij’s 2961 kb sequence
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