Interference 103,579
of the coding region of the PGBSS gene (VDX 10 and 2; HR 312 and
HDX 8).
XIV. We conclude that the DNA fragment of the 0-4964 bp
PGBSS gene which Hofvander identifies as SEQ ID No. 2 in the
claims of Hofvander’s involved application, depicts in HDX 8 and
HR 312, and either inserted or designated for insertion in the
genome of a potato plant in antisense direction, is 2549 bp in
length and includes a major fraction of the 1000-2000 bp segment,
the entire 2000-3000 segment, and a major fraction of the 3000-
4000 bp segment of the 0-4964 bp PGBSS gene depicted in VDX 15
and HDX 8. As best we can determine, the 5' end of the 2549 bp
fragment (Hofvander’s Antisense fragment II) starts at the 5'
HindIII end of the HindIII-SpeI fragment of the coding region of
the PGBSS gene or at the HpaI restriction site just before the 5'
HindIII end of the HindIII-SpeI fragment of the coding region of
the PGBSS gene and ends before the 3' SpeI end of the HindIII-
SpeI fragment of the coding region of the PGBSS gene (VDX 10
and 2; HR 312 and HDX 8). As best we can determine, the 2549 bp
fragment includes a major fraction of the HindIII-SpeI fragment
of the coding region of the PGBSS gene but excludes the SstI-SpeI
fragment at the 3' SpeI end of the HindIII-SpeI fragment of the
coding region of the PGBSS gene (VDX 10 and 2; HR 312 and HDX 8).
XV. As best we can determine, Hofvander’s 2549 bp SEQ ID
No. 2 and Hofvander’s 342 bp SEQ ID No. 1 either do not overlap
-75-
Page: Previous 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 Next
Last modified: November 3, 2007