Ex Parte MCGREGOR et al - Page 4




              Appeal No. 2002-0450                                                                                     
              Application No. 09/142,814                                                                               
              of substantially uniform thickness.   This forms a substantially spherical bead.   The non-              
              porous layer forms a substantially continuous coating over the core to substantially                     
              prevent cellular invasion of the core until the layer has fully degraded in the body.                    
              Specification, page 3.  In certain embodiments, the material of the invention may be a                   
              fluid, gel or paste comprising the coated beads.  Specification, page 4.                                 


              35 U.S.C. ' 102                                                                                          
                     Claims 1-8 stand rejected under 35 U.S.C. ' 102 as anticipated by Arnold.                         
                     It is the examiner=s position that (Answer, pages 3-4):                                           
                     Arnold discloses wound implant material comprising a plurality of one or                          
                     more bioabsorbable polymers such as polymers or copolymers of lactic                              
                     acid and/or glycolic acid, collagen, hyaluronic acid or cellulose derivatives                     
                     bound together by a bioabsorbable matrix .... Arnold=s microspheres                               
                     preferably have a diameter of 50 to 250 microns, are in solid, gel or                             
                     sponge form.  Arnold=s microspheres may further comprise a therapeutic                            
                     agent, such as fibronectin, a growth factor, or an antibiotic....   Arnold                        
                     specifically teaches the use of a second suitable bioabsorbable polymer                           
                     such as polylactic/polyglycolic acid or oxidized regenerated cellulose to                         
                     reinforce the integrity of the matrix....   Arnold discloses microspheres of                      
                     hyaluronic acid/collagen in a collagen matrix or mesh entity....   Therefore,                     
                     Arnold meets the limitations set forth in the instant claims.                                     
                     To anticipate a claim, a prior art reference must disclose every limitation of the                
              claimed invention, either explicitly or inherently.  In re Schreiber, 128 F.3d 1473, 1477,               
              44 USPQ2d 1429, 1431 (Fed. Cir. 1997).  Appellants argue the beads of Appellants=                        
              invention are not identical to Arnold=s matrix of bound together microspheres.                           




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