Ex Parte BECKER et al - Page 2


                Appeal No. 2001-0692                                                      Page 2                   
                Application No. 09/163,572                                                                         

                              (b)    determining the array location of each compound in each                       
                                     test zone;                                                                    
                              (c)    determining the response activity of the compounds in the                     
                                     arrays to the testing screen; and                                             
                              (d)    ascertaining the compounds that had a positive response to                    
                                     the testing screen.                                                           
                       9.     The method of claim 1 wherein the activity is the ability of                         
                              compounds to hybridize to a library of genes.                                        
                       23.    The method of claim 1 wherein the activity is to determine a                         
                              cholesteryl ester transfer protein inhibitor.                                        

                       The examiner relies on the following references:                                            
                Pomponi et al. (Pomponi)                 5,446,207           Aug. 29, 1995                         
                Evans et al. (Evans), “Physical mapping of complex genomes by cosmid                               
                multiplex analysis,” Proc. Natl. Acad. Sci. USA, Vol. 86, pp. 5030-5034 (1989)                     

                       Claims 1-4 and 9 stand rejected under 35 U.S.C. § 102(b) as anticipated                     
                by Evans.                                                                                          
                       Claims 8, 10, 13-33, 36, and 37 stand rejected under 35 U.S.C. § 103 as                     
                obvious in view of Evans and Pomponi.                                                              
                       Claims 1-4, 8-10, 13-33, 36, and 37 stand rejected under 35 U.S.C. § 112,                   
                second paragraph, as indefinite.                                                                   
                       We affirm the rejection for anticipation but reverse the rejections for                     
                obviousness and indefiniteness.                                                                    
                                                   Background                                                      
                       The specification discloses a method of simultaneously testing a large                      
                number of compounds in a biological assay.  The disclosed method starts with a                     





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