Ex Parte BECKER et al - Page 6


                Appeal No. 2001-0692                                                      Page 6                   
                Application No. 09/163,572                                                                         

                Fig. 2 multiwell plate grids with a single clone common to both plates.”                           
                Examiner’s Answer, page 4.  See also page 8:  “It is the examiner’s position that                  
                Evans teaches the presently claimed method of testing a plurality of compounds                     
                for activity.  In the wells of Evans, a plurality of compounds is added and their                  
                activity is determined, all simultaneously.  Note that the reaction of a probe being               
                positive or negative is an activity determination.”                                                
                       “It is well settled that a claim is anticipated if each and every limitation is             
                found either expressly or inherently in a single prior art reference.”  Celeritas                  
                Techs. Ltd. v. Rockwell Int’l Corp., 150 F.3d 1354, 1361, 47 USPQ2d 1516, 1522                     
                (Fed. Cir. 1998).  “[T]he description of a single embodiment of broadly described                  
                subject matter constitutes a description of the invention for anticipation                         
                purposes.”  In re Lukach, 442 F.2d 967, 970, 169 USPQ 795, 797 (CCPA 1971).                        
                       We agree with the examiner that Evans anticipates instant claim 1.  Claim                   
                1 is directed to a screening method in which a plurality of test compounds are                     
                placed into at least two arrays, each of which has a plurality of test zones;                      
                multiple compounds are placed into each test zone, and at least one identical                      
                compound is placed into each of the two arrays.  After the test compounds are                      
                placed into the arrays, the claimed method entails determining the location of                     
                each compound in the test zones of each array, determining the response activity                   
                of the compounds to the testing screen, and ascertaining which compounds had                       
                a positive response to the testing screen.                                                         
                       In the method disclosed by Evans, different DNA molecules (cosmids) are                     
                “organized as an ordered matrix.”  Abstract; see also Figure 2.  All of the cosmids                





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