Ex Parte BECKER et al - Page 3


                Appeal No. 2001-0692                                                      Page 3                   
                Application No. 09/163,572                                                                         

                set of “simple plates” which each contain test compounds arranged in a row-and-                    
                column grid.  See page 5, lines 6-12.  Thus, for example, a set of 10 simple                       
                plates might each contain a grid made up of 10 columns and 8 rows (80 test                         
                compounds per plate, or 800 test compounds in the set of 10 simple plates).  See                   
                id.                                                                                                
                       The compounds on the set of simple plates are combined to produce two                       
                “master plates,” known as the X master plate and the Y master plate.  See page                     
                5, lines 12-22.  To produce the X master plate, samples of each compound in a                      
                specific row of a specific plate are combined into a single, specific well in the X                
                plate.  Thus, for example, the first well of the first column of the X plate would                 
                contain a sample of each compound from columns 1 through 10 in the first row of                    
                plate 1, the second well in the first column of the X plate would contain a sample                 
                of each compound from the second row of plate 1, and so on.  In this way, the                      
                contents of each simple plate are represented in a specific column of the X                        
                master plate.                                                                                      
                       The Y master plate is produced by a different method.  The Y master plate                   
                is produced by taking a sample from the same location on each simple plate, and                    
                combining these ten samples into a single well in the same location on the Y                       
                plate.  Thus, for example, samples of the compound found in the first column of                    
                the first row of each of the ten simple plates are combined in the well in the first               
                column of the first row of the Y master plate.  Thus, “[b]oth the ‘X Master plate’                 
                and the ‘Y Master plate’ have 10 compounds in each well while each compound                        







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