Ex Parte BECKER et al - Page 10


                Appeal No. 2001-0692                                                     Page 10                   
                Application No. 09/163,572                                                                         

                Examining Procedure (MPEP) § 1002.02(c) (petitions relating to formal                              
                sufficiency and propriety of declarations under 37 CFR § 1.132 are decided by                      
                Technology Center Directors); § 1201 (“The line of demarcation between                             
                appealable matters for the Board of Patent Appeals and Interferences and                           
                petitionable matters for the Commissioner of Patents and Trademarks should be                      
                carefully observed.”).  Therefore, the Brussolo declaration is not properly a part                 
                of the record on appeal and we have not considered it.                                             
                3.  Obviousness                                                                                    
                       The examiner rejected claims 8, 10, 13-33, 36, and 37 as obvious in view                    
                of Evans and Pomponi.  The examiner relied on Evans for the disclosures                            
                discussed above.  The examiner cited Pomponi as teaching “an assay for CETP                        
                [cholesteryl ester transfer protein] in multiple 96-well microtiter plates to test for             
                inhibition of various compounds where the compounds were placed in the wells                       
                with appropriate dilution, a testing screen was performed and the inhibition was                   
                determined.”  Examiner’s Answer, page 6.  The examiner concluded that                              
                       [i]t would have been obvious to one or ordinary skill in the art at the                     
                       time the invention was made to screen compounds of any type in                              
                       the method of Evans because Pomponi teaches different                                       
                       compounds than Evans determined in arrays and one would have a                              
                       high expectation of success in employing known reaction formats to                          
                       perform known reactions.                                                                    
                Id.                                                                                                
                       “In proceedings before the Patent and Trademark Office, the Examiner                        
                bears the burden of establishing a prima facie case of obviousness based upon                      
                the prior art.”  In re Fritch, 972 F.2d 1260, 1265, 23 USPQ2d 1780, 1783 (Fed.                     






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