Appeal No. 2003-1804 Application No. 09/896,209 We have considered the applicant’s specification and claims, the applied prior art, and the positions of the examiner and appellant set forth in the examiner’s answer and appellant’s brief respectively. The examiner also rejected the appellant’s claims under 35 U.S.C. § 102, 35 U.S.C. § 103(a), and for double patenting, over Birkmayer I alone. However, we need not reach these rejections because we conclude that the combined prior art teaching establishes the prima facie obviousness under 35 U.S.C. § 103(a) of the invention defined by Claims 1-33. Appellant has presented no objective evidence of nonobviousness. Accordingly, we affirm the examiner’s final rejection of all pending claims under 35 U.S.C. § 103(a) in view of the combined prior art teachings. Discussion “The PTO has the burden under section 103 to establish a prima facie case of obviousness.” In re Fine, 837 F.2d 1071, 1073, 5 USPQ2d 1596, 1598 (Fed. Cir. 1988). Claims 1, 12, and 23 comprise administering to a human being an effective amount of NADH or NADPH or a physiologically acceptable compatible salt of NADH or NADPH. The Claim 1 method is effective for alleviating the effects of sleep deprivation. The Claim 12 method is effective for alleviating the effects of jet lag. The Claim 23 method is effective for enhancing attentiveness or reaction time. -3–Page: Previous 1 2 3 4 5 6 7 8 9 10 11 NextLast modified: November 3, 2007