Ex Parte Birkmayer - Page 3




          Appeal No. 2003-1804                                                        
          Application No. 09/896,209                                                  
               We have considered the applicant’s specification and claims,           
          the applied prior art, and the positions of the examiner and                
          appellant set forth in the examiner’s answer and appellant’s                
          brief respectively.  The examiner also rejected the appellant’s             
          claims under 35 U.S.C. § 102, 35 U.S.C. § 103(a), and for double            
          patenting, over Birkmayer I alone.  However, we need not reach              
          these rejections because we conclude that the combined prior art            
          teaching establishes the prima facie obviousness under 35 U.S.C.            
          § 103(a) of the invention defined by Claims 1-33.  Appellant has            
          presented no objective evidence of nonobviousness.  Accordingly,            
          we affirm the examiner’s final rejection of all pending claims              
          under 35 U.S.C. § 103(a) in view of the combined prior art                  
          teachings.                                                                  
                                     Discussion                                       
               “The PTO has the burden under section 103 to establish a               
          prima facie case of obviousness.”  In re Fine, 837 F.2d 1071,               
          1073, 5 USPQ2d 1596, 1598 (Fed. Cir. 1988).  Claims 1, 12, and 23           
          comprise administering to a human being an effective amount of              
          NADH or NADPH or a physiologically acceptable compatible salt of            
          NADH or NADPH.  The Claim 1 method is effective for alleviating             
          the effects of sleep deprivation.  The Claim 12 method is                   
          effective for alleviating the effects of jet lag.  The Claim 23             
          method is effective for enhancing attentiveness or reaction time.           

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