Appeal No. 2003-1804 Application No. 09/896,209 In our view, persons having ordinary skill in the art would have understood from Birkmayer I and Birkmayer II that NADH would alleviate symptoms related to fatigue, sleep deprivation, and jet lag. One of ordinary skill in the art at the time the invention was made would have understood that Birkmayer II also suggests administering NADH to any person to improve attentiveness and reaction time. Therefore, it would have been prima facie obvious at the time the claimed invention was made to alleviate the effects of sleep deprivation, alleviate the effects of jet lag, and/or enhance attentiveness or reaction time by administering NADH. Appellant’s arguments do not undermine the established prima facie case of obviousness. Appellant argues that Birkmayer I “fails to teach or suggest that the primarily mental symptoms of jet lag and/or sleep deprivation, such as decreased attentiveness or reaction time, could be successfully alleviated by the method disclosed in the Birkmayer ’259 patent.” (Appeal brief, page 10, second full paragraph). Appellant’s argument is unpersuasive. Appellant’s claims do not require alleviation and treatment of all effects of sleep deprivation or jet lag. Moreover, Birkmayer I teaches alleviation of symptoms such as inability to concentrate. (Birkmayer I, column 7, lines 38-48). -8–Page: Previous 1 2 3 4 5 6 7 8 9 10 11 NextLast modified: November 3, 2007