Ex Parte Birkmayer - Page 8




          Appeal No. 2003-1804                                                        
          Application No. 09/896,209                                                  
               In our view, persons having ordinary skill in the art would            
          have understood from Birkmayer I and Birkmayer II that NADH would           
          alleviate symptoms related to fatigue, sleep deprivation, and jet           
          lag.  One of ordinary skill in the art at the time the invention            
          was made would have understood that Birkmayer II also suggests              
          administering NADH to any person to improve attentiveness and               
          reaction time.  Therefore, it would have been prima facie obvious           
          at the time the claimed invention was made to alleviate the                 
          effects of sleep deprivation, alleviate the effects of jet lag,             
          and/or enhance attentiveness or reaction time by administering              
          NADH.                                                                       
               Appellant’s arguments do not undermine the established prima           
          facie case of obviousness.  Appellant argues that Birkmayer I               
          “fails to teach or suggest that the primarily mental symptoms of            
          jet lag and/or sleep deprivation, such as decreased attentiveness           
          or reaction time, could be successfully alleviated by the method            
          disclosed in the Birkmayer ’259 patent.”  (Appeal brief, page 10,           
          second full paragraph).  Appellant’s argument is unpersuasive.              
          Appellant’s claims do not require alleviation and treatment of              
          all effects of sleep deprivation or jet lag.  Moreover,                     
          Birkmayer I teaches alleviation of symptoms such as inability to            
          concentrate. (Birkmayer I, column 7, lines 38-48).                          


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