Ex Parte Birkmayer - Page 6




          Appeal No. 2003-1804                                                        
          Application No. 09/896,209                                                  
          Fatigue Syndrome likely would have been effective for treating              
          symptoms of jet lag and/or sleep deprivation.                               
               Moreover, Birkmayer II also suggests applicant’s claimed               
          inventions.   Birkmayer II teaches that NADH (ENADA) can be                 
          administered to improve the energy level and well-being of heathy           
          individuals and individuals with health problems.  (Birkmayer II,           
          page 23, fourth paragraph).  Birkmayer II states (Birkmayer II,             
          page 23, fourth paragraph):                                                 
                    ENADA is a natural approach to energy, drive and                  
               health.  ENADA (NADH) energizes both body and brain                    
               activity, improves alertness, concentration, emotion, drive,           
               hormone secretion and overall mood enhancement.  It helps              
               improve brain cell performance and helps keep cells alive              
               for a longer period of time.  The more ENADA (NADH) a cell             
               has available, the more energy it can produce to perform its           
               process efficiently.  ENADA (NADH) is available to everyone            
               whose lifestyle demands increased energy, vitality and                 
               mental activity.                                                       

          Birkmayer II discloses that effects observed after administering            
          NADH “included increased oxygen capacity, decreased reaction                
          time and greater mental acuity and alertness.”  (Birkmayer II,              
          page 25, first paragraph).                                                  
               Additionally, Birkmayer II teaches that NADH is useful for             
          treating persons suffering from fatigue.  Birkmayer II reports              
          recipients stating (Birkmayer II, page 41):                                 

                    On many mornings, I found it difficult to get up; my              
               body felt heavy and couldn’t wake up.  It was difficult                

                                         -6–                                          





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