Appeal No. 2005-0545 Application No. 09/989,019 l. 58-64): A still further object of the present invention is a treatment method designed to combat cellulitis and local fat overload and to improve the aesthetic appearance of a person, characterized by the application to the skin or oral administration of a composition containing at least one . . . lipolytic active principle. Soudant instructs (Soudant, col. 2, l. 3-7): Topical application of an anticellulitic agent may erase local accumulation of fat by lipolytic action. The best-known and most widespread method of stimulating lipolysis is by inhibiting phosphodiesterase to prevent or at least limit the rate of cyclic AMP breakdown. Thus, absent evidence sufficient to establish that the invention of Claim 8 is patentably distinct from the invention of Claims 1-7 and 9-11, the patentability of the method of treating cellulitis of Claim 8 by topical application of a formulation of Claims 1-7 and 9-11 reasonably appears to stand or fall with the patentability of formulation Claims 1-7 and 9-11, stated as useful for topical application to the skin of a woman evincing the cosmetic condition called cellulite, in view of the combined prior art teachings. One or more of the applied prior art references teaches that at least one of the components of the rejected formulation is a phosphodiesterase inhibitor and lipolytic. Thus, persons having ordinary skill in the art would reasonably have expected that such component could be topically applied to the skin to combat 5Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 NextLast modified: November 3, 2007