Ex Parte Regnier et al - Page 20




             Appeal No. 2005-1216                                                                                    
             Application No. 10/117,453                                                                              
             of the sample between adjacent surfaces and keep the polymers being synthesized                         
             thereon “substantially pure” or distinct from other samples.  See, e.g., col. 8, lines 12-              
             15.  That is, since Fodor discloses that the sample support surfaces are to be used for                 
             preparing diverse chemical sequences; i.e., the invention may be applied “for example,                  
             in the field of preparation of an oligomer, peptide, nucleic acid, oligosaccharide,                     
             phospholipid, polymer or drug congener preparation, especially to create sources of                     
             chemical diversity for use in screening for biological activity,” manifestly, the recessed              
             areas must inhibit transport of sample from one support surface to another in order to                  
             maintain sample integrity or purity.  Accordingly, in view of the foregoing, we find Fodor              
             teaches each and every element of the sample holder described in claim 30.6  In re                      
             Robertson, 169 F.3d at 745, 49 USPQ2d at 1950; Celeritas Techs. Ltd. v. Rockwell Int’l                  
             Corp., 150 F.3d at 1360, 47 USPQ2d at 1522; Verdegaal Bros., Inc. v. Union Oil Co.,                     
             814 F.2d at 631, 2 USPQ2d at 1053; Lindemann Maschinenfabrik GMBH v. American                           
             Hoist and Derrick Co., 730 F.2d at 1458, 221 USPQ at 485.                                               
                    In addition, as discussed above, Fodor discloses that the invention provides an                  
             “apparatus for the use of a substrate having a plurality of polymer sequences . . .                     
             [including] the preparation of molecules containing sequences of amino acids . . .                      


                    6 We point out that claim 30 does not require that the sample holder be used for                 
             any specific purpose.  Therefore, any prior art disclosure of a structure having a                      
             multiplicity of islands which are non-removably connected through a substrate wherein                   
             the islands have a sample support surface and are separated by a recessed area                          
             which inhibits transport of a sample between support surfaces, will anticipate the claim                
             regardless of its use.                                                                                  
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