Ex Parte Regnier et al - Page 22




             Appeal No. 2005-1216                                                                                    
             Application No. 10/117,453                                                                              
                    C.   Claims 34 and 35 are rejected as being unpatentable under 35 U.S.C. § 103                   
             in view of Hillenkamp I and II and Fodor.                                                               
                    For the reasons discussed above, we find that the Hillenkamp and Fodor patents                   
             anticipate the sample holder recited in claim 30.  With respect to Hillenkamp I, we                     
             further find that the patent discloses that the projections or islands of the sample holders            
             can comprise sample support surfaces having different shapes.  See, e.g., Hillenkamp I,                 
             col. 9, lines 36-42.  Attention is also directed to Figure 11 of Hillenkamp which                       
             exemplifies sample support surfaces which appear to be non-uniform or irregular.   With                 
             respect to Fodor, we further find that the patent discloses that the sample support                     
             surfaces can vary in shape “by way of the formation of trenches, v-grooves, mesa                        
             structures, or the like” (col. 11, lines 42-44) as well as in size (col. 9, lines 10-15).   In          
             view of these teachings, we find that Hillenkamp I and Fodor demonstrate that those of                  
             ordinary skill in the art would have understood that the islands and sample holder                      
             support surface can be varied in shape depending on the type and amount of sample to                    
             be assayed in order to optimize the result.  That is to say, we find that the shape of the              
             island and sample support surface is recognized in the art of sample holders as being a                 
             “result effective variable.”  In re Boesch, 617 F.2d 272, 276, 205 USPQ 215, 219 (CCPA                  
             1980)(“discovery of an optimum value of a result effective variable in a known process                  
             is ordinarily within the skill of the art”).  Thus, in our view, it                                     





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