Ex Parte Spencer et al - Page 3

            Appeal 2007-0082                                                                                 
            Application 10/171,498                                                                           



            Background                                                                                       
                   The claimed invention relates to a seed of a fertile, transgenic maize plant              
            which incorporates a nucleic acid sequence encoding phosphinothricin acetyl                      
            transferase (PAT).  The enzyme phosphinothricin acetyl transferase inactivates the               
            active ingredient in the herbicides bialphos, or phosphinothricin.  Phosphinothricin             
            inhibits glutamine synthase causing rapid accumulation of ammonia and cell death.                
            (Strauch, col. 1, ll. 13-35; see also, U.S. Patent No. 6,395,966, col. 3, ll. 7-16.)             
            Thus, the PAT gene confers herbicide resistance to a corn plant.                                 

            Issue                                                                                            
                   The issue in this case is whether Tomes and Strauch provide a reasonable                  
            expectation of successfully obtaining a seed of a fertile, transgenic maize plant,               
            said seed comprising a chromosomally incorporated nucleic acid sequence                          
            encoding PAT and capable of being cultivated to produce a transgenic maize plant                 
            having resistance to a herbicide comprising phosphinothricin.                                    

            Obviousness                                                                                      
                   Claims 39-45 stand rejected under 35 U.S.C. 103(a) as obvious over Tomes1                 

                                                                                                            
            1 U.S. Patent 6,258,999 B1 to Tomes et al., issued July 10, 2001, and has an                     
            effective filing date of June 10, 1988.  The Tomes patent issued from Application                
            No. 08/442,522 filed May 16, 1995 which was a divisional of Application No.                      
            08/319,352 filed on Oct. 6, 1994; which is a continuation of Application No.                     
            07/906,018 filed on June 26, 1992; which is a continuation of Application No.                    
            07/581,154 filed on Sept. 7, 1990; which is a continuation of Application No.                    
            07/205,155 filed on June 10, 1988.                                                               

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