Ex Parte Murphy et al - Page 18



               Appeal 2007-1378                                                                          
               Application 10/327,459                                                                    
           1   when becoming convinced an applicant has a point with respect to one of                   
           2   numerous rejections.  If the Examiner, at the Examiner’s Answer stage, had                
           3   harbored any doubt about enablement, we would have had both an                            
           4   enablement and obviousness rejection before us.  Moreover, on the merits of               
           5   the rejections before us, Rouhi seems to be a “generic” discussion about                  
           6   numerous problems and concerns in the pharmaceutical field.  While                        
           7   paroxetine hydrochloride and cefadroxil are mentioned (see page 30),                      
           8   neither are azithromycins—a fact which immediately can be confirmed by                    
           9   reference to the 2001 Physicians’ Desk Reference at pages 1003 and 3114.                  
         10    Appellants’ reliance on Rouhi is not persuasive when weighed against the                  
         11    explicit azithromycin teachings of Curatolo—a patent said to be owned by                  
         12    appellants’ assignee.  Curatolo convincingly shows that one skilled in the art            
         13    uses dry granulating or direct compression techniques to make azithromycin                
         14    tablets.  Rouhi does not appear to mention azithromycin.  For the reasons                 
         15    given, as applied to the facts of this case, we credit the more relevant                  
         16    teachings of Curatolo over the less relevant “teachings” of Rouhi.                        
         17          Appellants maintain that the Examiner has used an “obvious to try”                  
         18    standard.  According to appellants an “obvious to try” standard is not an                 
         19    appropriate standard.  Appeal Brief, pages 12-13 and 16-17.  This argument                
         20    goes nowhere.  The Examiner did not make an obviousness holding based on                  
         21    “obvious to try.”  Moreover, an “obvious to try” argument is often made                   
         22    when there is an issue of whether the evidence supports a finding that there              
         23    is a reasonable chance of success.  In re O’Farrell, 853 F.2d 894, 7 USPQ2d               
         24    1673 (Fed. Cir. 1988).  See also (1) In re Eli Lilly & Co., 902 F.2d 943, 945,            
         25    14 USPQ2d 1741, 1743 (Fed. Cir. 1990) (an "obvious-to-try" situation exists               

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