Appeal 2007-2213
Application 10/355,433
(a) depositing drops, at least some of which contain
probe precursors, onto the substrate surface so that the probe
precursors bind to the surface through a linker, wherein all of
the drops containing probe precursors contain the same
concentration of probe precursors; and
(b) repeating (a) multiple times wherein the probe
precursor deposited in a prior cycle becomes the linker for a
probe precursor deposited in a subsequent cycle, so as to form
the array;
wherein the deposited drops comprise an unblocked-
hydroxy free and unblocked-amino free polymer to enhance
viscosity, and wherein viscosity of different drops containing
different probe precursors at a same concentration is above
7 cps and the viscosities of the different drops containing
different probe precursors at the same concentration are all
within 2 cps of one another.
5. A method according to claim [1 wherein the
biopolymer probes comprise polynucleotide or peptide probes
and] wherein the drops comprise probe precursors and the
viscosity of the probe precursor containing drops when only the
viscosity enhancer is absent is below 9 cps.
7. A method according to claim 5 wherein sufficient
polymer is present to raise the viscosity of the drops comprising
probe precursors by at least 2 cps.
18. A method according to claim [1 wherein the
biopolymer probes comprise polynucleotide or peptide probes
and the method additionally comprises exposing the fabricated
array to a sample and], following exposure of the array to a
sample, reading the array.
19. A method comprising forwarding a result of a
reading obtained by the method of claim 18, to a remote
location.
42. A method of fabricating an array of biopolymer
probes bound to a surface of a substrate, comprising:
3
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