Appeal No. 94-2504 Application 07/963,676 of an injury to cells in mammalian tissue in vivo and treatment of epilepsy,” not “to compounds” as the examiner indicated. Moreover, as filed, Claims 2-16 were all dependent upon Claim 1 which generically defined the treating agent as “a cell membrane permeant calcium buffer.” Needless to say, our attempts to comprehend the examiner’s restriction requirement have been unsuccessful. In response to the restriction requirement (Paper No. 4, filed January 6, 1993), applicants interpreted the examiner’s restriction requirement as requiring restriction between (I) method Claims 1-16, (II) method Claims 23-25, (III) compound Claims 17-21, and (IV) composition Claim 22, and an election of a species of buffer. Accordingly, applicants elected the method of Claim 10 and BAPTA-AM as the species of buffer. In a second office action mailed February 5, 1993 (Paper No. 6), the examiner withdrew Claims 2-9 and 17-25 from consideration without explanation and indicated that Claims 1 and 10-16 would be examined. The examiner then summarily rejected Claims 1 and 10-16 as follows (Paper No. 6, p. 2): Claims 1 and 10-16 are rejected under 35 U.S.C. § 112, second paragraph, as being indefinite for failing to - 3 -Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 NextLast modified: November 3, 2007